The UT’s Estonian Genome Center and Finnish researchers discovered novel blood biomarkers related to mortality | University of Tartu
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Faculty of Arts and Humanities
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(+372) 737 5341
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Jakobi 2 - 116-121, 51014, Tartu
  • Dean's Office
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    Jakobi 2, 51003, Tartu
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    Jakobi 2, 51014, Tartu
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    Jakobi 2, III, rooms 309-352, 51014, Tartu
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    Ülikooli 18-310, 50090, Tartu
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    Lossi 3, 51003, Tartu
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    Posti 1, 71004, Viljandi
Faculty of Social Sciences
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(+372) 737 5957
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Lossi 36, 51003, Tartu
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    + 372 737 5900
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    Lossi 36, 51003, Tartu
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    Salme 1a, room 29, 50103, Tartu
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    Lossi 36, roomm 301, 51003, Tartu
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    J. Liivi 4, 50409, Tartu
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    Näituse 2, 50409, Tartu
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    Näituse 20, 50409, Tartu
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    Lossi 36, 51003, Tartu
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    Raekoja plats 2, 20307, Narva
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    Ringi 35, 80012, Pärnu
Faculty of Medicine
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(+372) 737 5326
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Ravila 19, 50411, Tartu
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    Biomeedikum, Ravila 19, 50411, Tartu
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    Nooruse 1, 50411, Tartu
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    Raekoja plats 6, 51003, Tartu
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    L. Puusepa 8, 51014, Tartu, Eesti
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    Ravila 19, 50411 Tartu
  • Institute of Sport Sciences and Physiotherapy
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    (+372) 737 5360
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    Jakobi 5-205, 51014, Tartu
Faculty of Science and Technology
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(+372) 737 5820
Faculty address: 
Vanemuise 46-208, 51014, Tartu
  • Dean's Office
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    Faculty address: 
    Vanemuise 46 - 208, 51014, Tartu
  • Institute of Computer Science
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    J. Liivi 2, 50409, Tartu
  • Estonian Marine Institute
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    Mäealuse 14, 12618, Tallinn
  • Institute of Physics
    Faculty address: 
    W. Ostwaldi Str 1, 50411, Tartu
  • Institute of Chemistry
    Faculty phone: 
    (+372) 737 5261
    Faculty address: 
    Ravila 14a, 50411, Tartu
  • Institute of Mathematics and Statistics
    Faculty phone: 
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    Faculty address: 
    J. Liivi 2, 50409, Tartu
  • Institute of Molecular and Cell Biology
    Faculty phone: 
    (+372) 737 5011
    Faculty address: 
    Riia 23, 23b-134, 51010, Tartu
  • Institute of Technology
    Faculty phone: 
    (+372) 737 4800
    Faculty address: 
    Nooruse 1, 50411, Tartu
  • Institute of Ecology and Earth Sciences
    Faculty phone: 
    (+372) 737 5835
    Faculty address: 
    Vanemuise 46, 51014, Tartu
Institutions
  • Library
    Faculty phone: 
    (+372) 737 5702
    Faculty address: 
    W.Struve 1, 50091, Tartu
  • Youth Academy
    Faculty phone: 
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    Faculty address: 
    Lossi 38, 51003, Tartu
  • Estonian Genome Center
    Faculty phone: 
    (+372) 737 4000
    Faculty address: 
    Riia 23b, 51010, Tartu
  • Museum
    Faculty phone: 
    (+372) 737 5674
    Faculty address: 
    Lossi 25, 51014, Tartu
  • University of Tartu Natural History Museum and Botanical Garden
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Support Units
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    Teatri väljak 3, 10143 Tallinn
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    Ülikooli 18a, 51014, Tartu
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    Jakobi 4, 51014, Tartu
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    Faculty address: 
    Ülikooli 18a, 51014, Tartu
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    Ülikooli 17-114, 51014, Tartu
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    Faculty address: 
    Ülikooli 18, ruum 210, 50090, Tartu
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    Faculty address: 
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    Faculty address: 
    Lossi 3, III korrus, 51003, Tartu
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    Ülikooli 18, rooms 302 and 304, 50090, Tartu
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Other Units
  • University of Tartu Academic Sports Club
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    W. Struve 1, 50091 Tartu
  • Tartu University Hospital
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    L. Puusepa 1a, 50406 Tartu
  • University of Tartu Foundation
    Faculty phone: 
    +372 737 5852
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    Ülikooli 18, 50090 Tartu
  • View all other units

Contacts of UT units

Faculty of Arts and Humanities
Faculty phone: 
(+372) 737 5341
Faculty address: 
Jakobi 2 - 116-121, 51014, Tartu
  • Dean's Office
    Faculty phone: 
    + 372 737 5341
    Faculty address: 
    Jakobi 2, rooms 116 - 121, 51014, Tartu
  • Institute of History and Archaeology
    Faculty phone: 
    (+372) 737 5651
    Faculty address: 
    Jakobi 2, 51003, Tartu
  • Institute of Estonian and General Linguistics
    Faculty phone: 
    (+372) 737 5221
    Faculty address: 
    Jakobi 2, 51014, Tartu
  • Institute of Philosophy and Semiotics
    Faculty phone: 
    (+372) 737 5314
    Faculty address: 
    Jakobi 2, III, rooms 309-352, 51014, Tartu
  • Institute of Cultural Research
    Faculty phone: 
    (+372) 737 5223
    Faculty address: 
    Ülikooli 16, 51003, Tartu
  • School of Theology and Religious Studies
    Faculty phone: 
    (+372) 737 5301
    Faculty address: 
    Ülikooli 18-310, 50090, Tartu
  • College of Foreign Languages and Cultures
    Faculty address: 
    Lossi 3, 51003, Tartu
  • Viljandi Culture Academy
    Faculty phone: 
    (+372) 435 5232
    Faculty address: 
    Posti 1, 71004, Viljandi
Faculty of Social Sciences
Faculty phone: 
(+372) 737 5957
Faculty address: 
Lossi 36, 51003, Tartu
  • Dean's Office
    Faculty phone: 
    + 372 737 5900
    Faculty address: 
    Lossi 36, 51003, Tartu
  • Institute of Education
    Faculty phone: 
    (+372) 737 6440
    Faculty address: 
    Salme 1a, room 29, 50103, Tartu
  • Johan Skytte Institute of Political Studies
    Faculty phone: 
    (+372) 737 5582
    Faculty address: 
    Lossi 36, roomm 301, 51003, Tartu
  • School of Economics and Business Administration
    Faculty phone: 
    (+372) 737 6310
    Faculty address: 
    J. Liivi 4, 50409, Tartu
  • Institute of Psychology
    Faculty phone: 
    (+372) 737 5902
    Faculty address: 
    Näituse 2, 50409, Tartu
  • School of Law
    Faculty phone: 
    (+372) 737 5390
    Faculty address: 
    Näituse 20, 50409, Tartu
  • Institute of Social Studies
    Faculty phone: 
    (+372) 737 5188
    Faculty address: 
    Lossi 36, 51003, Tartu
  • Narva College
    Faculty phone: 
    (+372) 740 1900
    Faculty address: 
    Raekoja plats 2, 20307, Narva
  • Pärnu College
    Faculty phone: 
    (+372) 445 0520
    Faculty address: 
    Ringi 35, 80012, Pärnu
Faculty of Medicine
Faculty phone: 
(+372) 737 5326
Faculty address: 
Ravila 19, 50411, Tartu
  • Dean's Office
    Faculty phone: 
    (+372) 737 5326
    Faculty address: 
    Ravila 19, 50411, Tartu
  • Institute of Biomedicine and Translational Medicine
    Faculty phone: 
    +(372) 737 4210
    Faculty address: 
    Biomeedikum, Ravila 19, 50411, Tartu
  • Institute of Pharmacy
    Faculty phone: 
    (+372) 737 5286
    Faculty address: 
    Nooruse 1, 50411, Tartu
  • Institute of Dentistry
    Faculty phone: 
    (+372) 731 9856
    Faculty address: 
    Raekoja plats 6, 51003, Tartu
  • Institute of Clinical Medicine
    Faculty phone: 
    (+372) 737 5323
    Faculty address: 
    L. Puusepa 8, 51014, Tartu, Eesti
  • Institute of Family Medicine and Public Health
    Faculty phone: 
    (+372) 737 4190
    Faculty address: 
    Ravila 19, 50411 Tartu
  • Institute of Sport Sciences and Physiotherapy
    Faculty phone: 
    (+372) 737 5360
    Faculty address: 
    Jakobi 5-205, 51014, Tartu
Faculty of Science and Technology
Faculty phone: 
(+372) 737 5820
Faculty address: 
Vanemuise 46-208, 51014, Tartu
  • Dean's Office
    Faculty phone: 
    (+372) 737 5820
    Faculty address: 
    Vanemuise 46 - 208, 51014, Tartu
  • Institute of Computer Science
    Faculty phone: 
    (+372) 737 5445
    Faculty address: 
    J. Liivi 2, 50409, Tartu
  • Estonian Marine Institute
    Faculty phone: 
    (+372) 671 8902
    Faculty address: 
    Mäealuse 14, 12618, Tallinn
  • Institute of Physics
    Faculty address: 
    W. Ostwaldi Str 1, 50411, Tartu
  • Institute of Chemistry
    Faculty phone: 
    (+372) 737 5261
    Faculty address: 
    Ravila 14a, 50411, Tartu
  • Institute of Mathematics and Statistics
    Faculty phone: 
    (+372) 737 5860
    Faculty address: 
    J. Liivi 2, 50409, Tartu
  • Institute of Molecular and Cell Biology
    Faculty phone: 
    (+372) 737 5011
    Faculty address: 
    Riia 23, 23b-134, 51010, Tartu
  • Institute of Technology
    Faculty phone: 
    (+372) 737 4800
    Faculty address: 
    Nooruse 1, 50411, Tartu
  • Institute of Ecology and Earth Sciences
    Faculty phone: 
    (+372) 737 5835
    Faculty address: 
    Vanemuise 46, 51014, Tartu
Institutions
  • Library
    Faculty phone: 
    (+372) 737 5702
    Faculty address: 
    W.Struve 1, 50091, Tartu
  • Youth Academy
    Faculty phone: 
    (+372) 737 5581
    Faculty address: 
    Lossi 38, 51003, Tartu
  • Estonian Genome Center
    Faculty phone: 
    (+372) 737 4000
    Faculty address: 
    Riia 23b, 51010, Tartu
  • Museum
    Faculty phone: 
    (+372) 737 5674
    Faculty address: 
    Lossi 25, 51014, Tartu
  • University of Tartu Natural History Museum and Botanical Garden
    Faculty phone: 
    (+372) 737 6076
    Faculty address: 
    Vanemuise 46, 51014, Tartu
Support Units
  • Administrative Office
    Faculty phone: 
    (+372) 737 5606
    Faculty address: 
    Ülikooli 18a, 51014, Tartu
  • University Office in Tallinn
    Faculty phone: 
    +372 737 6600
    Faculty address: 
    Teatri väljak 3, 10143 Tallinn
  • Estates Office
    Faculty phone: 
    (+372) 737 5137
    Faculty address: 
    Ülikooli 18a, 51014, Tartu
  • Finance Office
    Faculty phone: 
    (+372) 737 5125
    Faculty address: 
    Jakobi 4, 51014, Tartu
  • Information Technology Office
    Faculty phone: 
    (+372) 737 6000, arvutiabi: 737 5500
    Faculty address: 
    Ülikooli 18a, 51014, Tartu
  • Internal Audit Office
    Faculty address: 
    Ülikooli 17-114, 51014, Tartu
  • Marketing and Communication Office
    Faculty phone: 
    (+372) 737 5687
    Faculty address: 
    Ülikooli 18, ruum 210, 50090, Tartu
  • Office of Academic Affairs
    Faculty phone: 
    (+372) 737 6215
    Faculty address: 
    Ülikooli 18, 50090, Tartu
  • Office of Research and Development
    Faculty phone: 
    (+372) 737 6192
    Faculty address: 
    Lossi 3, III korrus, 51003, Tartu
  • Human Resources Office
    Faculty phone: 
    (+372) 737 5145
    Faculty address: 
    Ülikooli 18, rooms 302 and 304, 50090, Tartu
  • Rector's Strategy Office
    Faculty phone: 
    (+372) 737 5600
    Faculty address: 
    Ülikooli 18, 51014, Tartu
  • Student Council
    Faculty phone: 
    (+372) 737 5400
    Faculty address: 
    Ülikooli 18b, 51014, Tartu
Other Units
  • University of Tartu Academic Sports Club
    Faculty phone: 
    +372 737 5371
    Faculty address: 
    Ujula 4, 51008 Tartu
  • Tartu Student Village
    Faculty phone: 
    +372 740 9959
    Faculty address: 
    Narva mnt 25, 51013 Tartu
  • Tartu Students’ Club
    Faculty phone: 
    +372 730 2400
    Faculty address: 
    Kalevi 24, 51010 Tartu
  • University of Tartu Press
    Faculty phone: 
    +372 737 5945
    Faculty address: 
    W. Struve 1, 50091 Tartu
  • Tartu University Hospital
    Faculty address: 
    L. Puusepa 1a, 50406 Tartu
  • University of Tartu Foundation
    Faculty phone: 
    +372 737 5852
    Faculty address: 
    Ülikooli 18, 50090 Tartu
  • View all other units

The UT’s Estonian Genome Center and Finnish researchers discovered novel blood biomarkers related to mortality

The Estonian Genome Center of the University and Tartu and the researchers in the Institute for Molecular Medicine Finland used a new technology to discover four mortality-related biomarkers that may in the future prove a valuable indicator on estimating the health state of people and determining the best treatment.

The survey included more than 10 000 gene donors of the Estonian Genome Center whose blood plasma was used to determine the values of 106 biomarkers, using the Nuclerar Magnetic Resonance (NMR) Spectroscopy technology in the collaborations with Finnish researchers. These biomarkers are mostly concentrations of various substances (proteins, amino acids) in the blood.

The causes of death have been determined for a little more than 2000 now-deceased individuals from the 52 000 gene donors in the UT’s Biobank on the basis of the Estonian Causes of Death Registry. This information is extremely valuable to researchers as it has enabled to compare the data from the registry with samples taken during the person’s lifetime, using an innovative nuclear magnetic resonance technology developed in Finland.

The results were surprising, because an unexpectedly strong connection between four biomarkers and mortality was established. Surprisingly, none of these markers forecast any specific disease, but the similar associations became evident for different disease-related causes of death. The fact that the finding was not a coincidence was proven by an analysis of the same indicators on 8000 individuals in the Finnish Finrisk97 survey. In the survey repeated on Finns, the same strong connection between the four biomarkers and mortality emerged. The associations remained unchanged for Estonian and Finnish cohorts even after removing individuals with a known chronic life-threatening disease from the data.

“Obviously, before it is possible to implement the research results in practice, it is necessary to conduct additional scientific research and study carefully the diseases that these high-risk individuals suffer from and what the awareness of these four markers would give us in addition to what we already know,” commented Krista Fischer, Senior Research Fellow of the UT’s Estonian Genome Center. “At the moment, we cannot claim with full certainty that the high-risk individuals differentiated on the basis of these four markers would not have been under heightened medical attention on other reasons, but there is plenty of reason to continue deeper research into the subject,” said Fischer.

Additional information: Senior Research Fellow in the Estonian Genome Center of the University of Tartu, 737 4042, 515 3679, e-mail:krista.fischer [ät] ut.ee.

Virge Tamme
Press Officer of the UT
Phone: +372 737 5683
Mobile: +372 5815 5392
E-mail: virge.tamme [ät] ut.ee
www.ut.ee