The lab of professor Tambet Teesalu uses phage display screens to identify homing peptides that bind to specific targets in the vasculature. Corresponding synthetic peptides are explored for targeting drugs, biologicals, and nanoparticles into tumors to increase their therapeutic index. Our scope includes understanding the molecular interactions involved to drive specificity and activity, focusing on Tumor Penetrating Peptides (TPP) that trigger bulk extravascular transport in the tumor tissue. More info.
Estonian Biobank is the population-based biobank of the Estonian Genome Center at the University of Tartu. The cohort size is currently 51,535 gene donors (≥18 years of age), which closely reflects the age, sex and geographical distribution of the Estonian population.
Estonians represent 83%, Russians 14%, and other nationalities 3% of all participants. More info.
For metallurgical applications where superior mechanical and corrosion resistance is desired, the University of Tartu offers a solution. Our team at the Laboratory of Thin Film Technology proposes a novel surface sealing layer that is resistant to both mechanical and chemical damage. The method is suitable for most metals and covers any surface geometry with a high-quality layer with uniform density. More info.
High Performance Liquid Chromatography/ Mass Spectrometry analysis of real-world biological substances in difficult matrices is often presented with problems with low signal to noise ratio, high limits of detection etc. To overcome this, expensive or difficult preparation or expensive technologies have to be used, raising the cost in time and money for such analyses. The scientists at the University of Tartu have devised a new and improved design for an electrospray inlet source nebulizer for an HPLC-MS interface that offers significant gain of signal, a raise in signal quality and a greater suppression of matrix effect as compared to ordinary atomizers at a lower costs. More info.
Estonian Electronic Microbial dataBase
EEMB (Estonian Electronic Microbial dataBase) is an electronic database of Estonian National Collection of Microbes that currently hosts three collections of microorganisms:
The strains preserved in the collection as well as all information about them are freely available for use for academic research (non-commercial purposes) within the institution.
The strains and other materials preserved in the collection as well as the information about them are accessible for academic research (noncommercial purposes) within the institution.
The strains and other materials preserved in the collection as well as the information about them are accessible for scientific research within the company. The microbe strains in the collection are handed over after an agreement between the head of the collection and the researcher that submitted the samples.