Aet Saar „Acute myocardial infarction in Estonia 2001–2014: towards risk based prevention and management“

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View all other units

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Date:

13.09.2019 - 14:00

On 13. September 2019 Aet Saar will defend her doctoral thesis „Aet Saar, „Acute myocardial infarction in Estonia 2001–2014: towards risk based prevention and management“.

Supervisors:
professor Jaan Eha, UT
research fellow Tiia Ainla, UT
research fellow Toomas Marandi, UT
professor Krista Fischer, UT

Opponent:
professor emeritus Markku Sakari Nieminen, Medical Faculty, University of Helsinki, Finland

Summary:
Mortality from cardiovascular disease, more specifically ischaemic heart disease and myocardial infarction, has shown substiantial decrease over the last decades in Estonia, but remains higher than an European average. More effective prevention and improved treatment after MI should be a priority to achieve better outcomes.
The cornerstone of prevention is identifying the highest risk individuals and treating them to reduce the risk of developing myocardial infarction. The intensity of preventive therapy should match the individual’s risk level – higher risk warrants more intensive treatment and guidelines recommend using risk scores for risk estimation. However, the predictive ability of risk scores has not been previously evaluated in Estonia. The current study found that the US PCE (Pooled Cohort Equations) and European SCORE performed at acceptable level in their original form and should be used for guiding management decisions in the prevention of cardiovascular disease. The UK QRISK2 markedly underestimated the risk and requires modification prior to use.
There has been an increase in the use of guideline-recommended therapies in myocardial infarction treatment over the period of 2001–2014 in Estonia. The current study showed an improved survival after myocardial infarction over the same time course, which was seen despite the increased mean age of the patients and rising burden of other diseases. Paradoxically, the improvement in treatment quality was more pronounced in patients with lower baseline mortality risk, while patients with higher mortality risk received less guideline-recommended treatments. The study also demonstrated the equalization of treatment quality between Estonian secondary and tertiary care hospitals – by the year 2011 the prognosis did not depend on the hospital type where a patient with myocardial infarction was initially hospitalized.

Location:

Ülikooli 18, Senate hall

URL:

hdl.handle.net/10062/64801

Event category:

Defence

M	T	W	T	F	S	S
		1 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	2 Madis Rahu „Structure and blood supply of the postero-superior part of the shoulder joint capsule with implementation of surgical treatment after anterior traumatic dislocation“ Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	3 Martin Maide „Influence of the microstructure and chemical composition of the fuel electrode on the electrochemical performance of reversible solid oxide fuel cell“ Physicum seminar: Oliver Shorttle "Tracing volatiles from protoplanetary disks through to planets" Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	4 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	5 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral
6 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	7 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	8 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	9 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	10 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	11 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	12 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral
13 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	14 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	15 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	16 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	17 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	18 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	19 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral
20 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	21 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	22 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	23 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	24 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	25 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	26 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral
27 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	28 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	29 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral	30 Rauno Thomas Moss Exhibition „ANATOMICAL ILLUSTRATIONS“ Opening on 25 February at 4 PM Exhibition dedicated to the Estonian national university “Estonia of Ideals. 100 Years of Quests” Estonia's National University 100: Photo exhibition “Put on Your Thinking Cap! The Hundred Faces of the University of Tartu” Aarne Maasik’s Photos of Tartu Cathedral

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Aet Saar „Acute myocardial infarction in Estonia 2001–2014: towards risk based prevention and management“

April