Anne-Mai Ilumäe „Genetic history of the Uralic-speaking peoples as seen through the paternal haplogroup N and autosomal variation of northern Eurasians“

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View all other units

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Date:

12.11.2019 - 10:15

On 12 November at 10:15 Anne-Mai Ilumäe will defend her doctoral theis „Genetic history of the Uralic-speaking peoples as seen through the paternal haplogroup N and autosomal variation of northern Eurasians“.

Supervisors:
Senior Research Fellow Kristiina Tambets, Senior Research Fellow of Population Genetics, University of Tartu
Senior Research Fellow Siiri Rootsi, Senior Research Fellow of Population Genetics, University of Tartu
Professor of Archaeogenetics, Institute of Molecular and Cell Biology, University of Tartu

Opponent:
Associate Professor Beniamino Trombetta, PhD, bioloogia ja biotehnoloogia osakond “C. Darwin”, University of Sapienza ülikool, Italy

Kokkuvõte
The Uralic linguistic family has been postulated for more than a hundred years with a current distribution area spanning from Europe to West Siberia. The prehistory of Uralic languages and their speakers has been under scrutiny of several generations of scientists from a variety of scientific fields. Numerous hypotheses have been proposed regarding their common origin, dispersal routes and possible homeland, but these questions continue to remain scientifically disputable.

A clear disruptor in the pattern of geography-dependent distribution of Y-chromosomal paternal lineages is haplogroup N that unites populations across entire north Eurasia and describes a fair share of Uralic-speaking males in both northeastern Europe and west Siberia. First aim of this thesis was to apply novel DNA re-sequencing approach to resolve the inner phylogenetic structure of haplogroup N and estimate coalescent ages along with geographic distribution of its inner subclades. Second aim was to test for a common autosomal genetic substrate between Uralic speakers using novel statistical methods.

The results suggest hg N to initially originate from North China or Mainland Southeast Asia and contain several novel subclades with distinct phylogeographic spread. One such subclade, N3a3’6 within subhaplogroup N3, displays an expansion time of 5000 years, but has a remarkably wide geographic distribution ranging from the eastern shores of the Baltic Sea to Mongolia and Pacific Russian Beringia, encompassing a considerate fraction of men from all major linguistic families in north Eurasia.

Whole genome data shows a small, yet significant autosomal genetic component of possible Siberian ancestry shared between most of the Uralic-speaking populations, suggesting a migratory contribution to the dispersal of the languages. This component is part of a broader eastern influence on the genepool of modern northern Europe and was probably not limited to the spread of extant Uralic languages.

Location:

Riia 23b/2-105

URL:

https://dspace.ut.ee/handle/10062/66492

Event category:

Defence

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Anne-Mai Ilumäe „Genetic history of the Uralic-speaking peoples as seen through the paternal haplogroup N and autosomal variation of northern Eurasians“

September