Veiko Vengerfeldt „Apical periodontitis: prevalence and etiopathogenetic aspects“ | University of Tartu

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Contacts of UT units

Faculty of Arts and Humanities
Faculty phone: 
+372 737 5341
Faculty address: 
Jakobi 2, rooms 116–121, 51005 Tartu
  • Dean's Office
    Faculty phone: 
    + 372 737 5341
    Faculty address: 
    Jakobi 2, rooms 116–121, 51005 Tartu
  • Institute of History and Archaeology
    Faculty phone: 
    +372 737 5651
    Faculty address: 
    Jakobi 2, 51005 Tartu
  • Institute of Estonian and General Linguistics
    Faculty phone: 
    +372 737 5221
    Faculty address: 
    Jakobi 2, 51005 Tartu
  • Institute of Philosophy and Semiotics
    Faculty phone: 
    +372 737 5314
    Faculty address: 
    Jakobi 2, rooms 309–352, 51005 Tartu
  • Institute of Cultural Research
    Faculty phone: 
    (+372) 737 5223
    Faculty address: 
    Ülikooli 16, 51003 Tartu
  • School of Theology and Religious Studies
    Faculty phone: 
    +372 737 5301
    Faculty address: 
    Ülikooli 18–310, 50090 Tartu
  • College of Foreign Languages and Cultures
    Faculty address: 
    Lossi 3, 51003 Tartu
  • Viljandi Culture Academy
    Faculty phone: 
    +372 435 5232
    Faculty address: 
    Posti 1, 71004 Viljandi
Faculty of Social Sciences
Faculty phone: 
+372 737 5957
Faculty address: 
Lossi 36, 51003 Tartu
  • Dean's Office
    Faculty phone: 
    + 372 737 5900
    Faculty address: 
    Lossi 36, 51003 Tartu
  • Institute of Education
    Faculty phone: 
    +372 737 6440
    Faculty address: 
    Salme 1a–29, 50103 Tartu
  • Johan Skytte Institute of Political Studies
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    Faculty address: 
    Lossi 36–301, 51003 Tartu
  • School of Economics and Business Administration
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    J. Liivi 4, 50409 Tartu
  • Institute of Psychology
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    Näituse 2, 50409 Tartu
  • School of Law
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  • Institute of Social Studies
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  • Narva College
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  • Dean's Office
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  • Institute of Biomedicine and Translational Medicine
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  • Institute of Pharmacy
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  • Institute of Dentistry
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    Raekoja plats 6, 51003 Tartu
  • Institute of Clinical Medicine
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    L. Puusepa 8, 50406 Tartu
  • Institute of Family Medicine and Public Health
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    Faculty address: 
    Ravila 19, 50411 Tartu
  • Institute of Sport Sciences and Physiotherapy
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    Faculty address: 
    Jakobi 5–205, 51005 Tartu
Faculty of Science and Technology
Faculty phone: 
+372 737 5820
Faculty address: 
Vanemuise 46–208, 51005 Tartu
  • Dean's Office
    Faculty phone: 
    +372 737 5820
    Faculty address: 
    Vanemuise 46–208, 51005 Tartu
  • Institute of Computer Science
    Faculty phone: 
    +372 737 5445
    Faculty address: 
    J. Liivi 2, 50409 Tartu
  • Estonian Marine Institute
    Faculty phone: 
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    Faculty address: 
    Mäealuse 14, 12618 Tallinn
  • Institute of Physics
    Faculty address: 
    W. Ostwaldi 1, 50411 Tartu
  • Institute of Chemistry
    Faculty phone: 
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    Faculty address: 
    Ravila 14a, 50411 Tartu
  • Institute of Mathematics and Statistics
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    Faculty address: 
    J. Liivi 2, 50409 Tartu
  • Institute of Molecular and Cell Biology
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    Riia 23, 23b–134, 51010 Tartu
  • Tartu Observatory
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  • Institute of Technology
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    Nooruse 1, 50411 Tartu
  • Institute of Ecology and Earth Sciences
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    Faculty address: 
    Vanemuise 46, 51003 Tartu
Institutions
  • Library
    Faculty phone: 
    +372 737 5702
    Faculty address: 
    W. Struve 1, 50091 Tartu
  • Youth Academy
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    +372 737 5581
    Faculty address: 
    Uppsala 10, 51003 Tartu
  • Institute of Genomics
    Faculty phone: 
    +372 737 4000
    Faculty address: 
    Riia 23b, 51010 Tartu
  • Museum
    Faculty phone: 
    +372 737 5674
    Faculty address: 
    Lossi 25, 51003 Tartu
  • University of Tartu Natural History Museum and Botanical Garden
    Faculty phone: 
    +372 737 6076
    Faculty address: 
    Vanemuise 46, 51003 Tartu
Support Units
  • Administrative Office
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    Faculty address: 
    Ülikooli 18a, 51005 Tartu
  • Centre for Entrepreneurship and Innovation
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    +372 737 6339
    Faculty address: 
    Lossi 3, III floor, 51003 Tartu
  • University Office in Tallinn
    Faculty phone: 
    +372 737 6600
    Faculty address: 
    Teatri väljak 3, 10143 Tallinn
  • Estates Office
    Faculty phone: 
    +372 737 5137
    Faculty address: 
    Ülikooli 18a, 51005 Tartu
  • Finance Office
    Faculty phone: 
    +372 737 5125
    Faculty address: 
    Jakobi 4, 51005 Tartu
  • Grant Office
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    +372 737 6215
    Faculty address: 
    Lossi 3, III floor, 51003 Tartu
  • Information Technology Office
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    Faculty address: 
    Ülikooli 18a, 51005 Tartu
  • Human Resources Office
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    Faculty address: 
    Ülikooli 18, rooms 302 and 304, 50090 Tartu
  • Internal Audit Office
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    Ülikooli 17–103, 51005 Tartu
  • Marketing and Communication Office
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    +372 737 5687
    Faculty address: 
    Ülikooli 18, rooms 102, 104, 209, 210, 50090 Tartu
  • Office of Academic Affairs
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    +372 737 5620
    Faculty address: 
    Ülikooli 18, 50090 Tartu
  • Procurement Office
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    +372 737 6632
    Faculty address: 
    Ülikooli 18a, 51005 Tartu
  • Rector's Strategy Office
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    Faculty address: 
    Ülikooli 18, 50090 Tartu
  • Student Council
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    Faculty address: 
    Ülikooli 18b, 51005 Tartu
Other Units
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    Faculty address: 
    Ujula 4, 51008 Tartu
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  • Tartu Students’ Club
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    Faculty address: 
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  • University of Tartu Press
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    Faculty address: 
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  • Tartu University Hospital
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  • University of Tartu Foundation
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  • View all other units

Veiko Vengerfeldt „Apical periodontitis: prevalence and etiopathogenetic aspects“

Date: 
15.11.2018 - 15:00

On 15 November at 15 Veiko Vengerfeldt will defend his doctoral thesis „Apical periodontitis: prevalence and etiopathogenetic aspects“,

Supervisors:
Professor Reet Mändar (dr. med. (meditsiin)), Institute of Biomedicine and Translational Medicine, University of Tartu
Professor Mare Saag (knd (meditsiin)), Institute of Biomedicine and Translational Medicine, University of Tartu
Associate Professor Tiiu Kullisaar (knd (bioloogia)), Institute of Biomedicine and Translational Medicine, University of Tartu

Opponent:
Professor Vytautė Pečiulienė (PhD), Institute of Dentistry, Faculty of Medicine, Vilnius University

Summary:
Apical periodontitis (AP) is an inflammatory disease around the apex of a tooth root that is caused by infection in root canal system. AP can be considered a sequela of advanced dental caries, and it is radiologically visible as hard tissue destruction around the apex of the tooth root. AP is a widespread condition all around the world and its prevalence is associated with age, gender, level of previous dental diseases and treatment and socioeconomic status of the region. The general aim of the present thesis was to clarify the prevalence, determining factors and etiopathogentic aspects of AP among Estonian population.

To clarify the prevalence of AP we analyzed radiographs of 6552 patient, we described and evaluated all teeth and their status. AP was diagnosed over half of the patients and we found a strong correlation between AP and previous dental diseases as well as the quality of previous dental treatment. The prevalence of AP was considerably lower in patients with high quality dental treatment.

Microbial samples were collected from 12 root canals, DNA was isolated and the bacteria were characterized. The communities were individually different but anaerobic bacteria predominated as the rule. We discovered several hard to cultivate and even some not yet discovered spices from root canals. Therefore, the microbiological analysis of the root canal content in case of endodontic pathologies is meaningless, and the treatment measures must be directed against wide spectrum of aerobic and anaerobic bacteria.

To measure oxidative stress (OxS), the saliva and root canal samples of 86 patients were analyzed. OxS levels were elevated in patients with endodontic pathologies compared to healthy subjects. OxS appeared to be an important pathogenetic mechanism in several endodontic pathologies being significantly associated with essential clinical markers like dental pain and bone destruction area around the apex of the tooth.

Location: 
Linkberg auditorium, Puusepa 8
Event category: