Inaugural lecture by Professor Kalle Kisand on relations between immune system and diabetes mellitus | University of Tartu

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Contacts of UT units

Faculty of Arts and Humanities
Faculty phone: 
+372 737 5341
Faculty address: 
Jakobi 2, rooms 116–121, 51005 Tartu
  • Dean's Office
    Faculty phone: 
    + 372 737 5341
    Faculty address: 
    Jakobi 2, rooms 116–121, 51005 Tartu
  • Institute of History and Archaeology
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    Faculty address: 
    Jakobi 2, 51005 Tartu
  • Institute of Estonian and General Linguistics
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    Jakobi 2, 51005 Tartu
  • Institute of Philosophy and Semiotics
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    Jakobi 2, rooms 309–352, 51005 Tartu
  • Institute of Cultural Research
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    Ülikooli 16, 51003 Tartu
  • School of Theology and Religious Studies
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    +372 737 5301
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    Ülikooli 18–310, 50090 Tartu
  • College of Foreign Languages and Cultures
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    Lossi 3, 51003 Tartu
  • Viljandi Culture Academy
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    Posti 1, 71004 Viljandi
Faculty of Social Sciences
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Lossi 36, 51003 Tartu
  • Dean's Office
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  • Institute of Education
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  • Johan Skytte Institute of Political Studies
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    Lossi 36–301, 51003 Tartu
  • School of Economics and Business Administration
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  • Institute of Psychology
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  • Institute of Biomedicine and Translational Medicine
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  • Institute of Pharmacy
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  • Institute of Dentistry
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  • Institute of Clinical Medicine
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  • Institute of Family Medicine and Public Health
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  • Institute of Sport Sciences and Physiotherapy
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Faculty of Science and Technology
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Vanemuise 46–208, 51014 Tartu
  • Dean's Office
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    Faculty address: 
    Vanemuise 46–208, 51005 Tartu
  • Institute of Computer Science
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    J. Liivi 2, 50409 Tartu
  • Estonian Marine Institute
    Faculty phone: 
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  • Institute of Physics
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  • Institute of Mathematics and Statistics
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    J. Liivi 2, 50409 Tartu
  • Institute of Molecular and Cell Biology
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  • Tartu Observatory
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  • Institute of Technology
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  • Institute of Ecology and Earth Sciences
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Institutions
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    Faculty address: 
    W. Struve 1, 50091 Tartu
  • Youth Academy
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    Faculty address: 
    Uppsala 10, 51003 Tartu
  • Institute of Genomics
    Faculty phone: 
    +372 737 4000
    Faculty address: 
    Riia 23b, 51010 Tartu
  • Museum
    Faculty phone: 
    +372 737 5674
    Faculty address: 
    Lossi 25, 51003 Tartu
  • University of Tartu Natural History Museum and Botanical Garden
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    Faculty address: 
    Vanemuise 46, 51003 Tartu
Support Units
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    Ülikooli 18a, 51005 Tartu
  • Centre for Entrepreneurship and Innovation
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    Faculty address: 
    Lossi 3, III floor, 51003 Tartu
  • University Office in Tallinn
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    Faculty address: 
    Teatri väljak 3, 10143 Tallinn
  • Estates Office
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    Faculty address: 
    Ülikooli 18a, 51005 Tartu
  • Finance Office
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    +372 737 5125
    Faculty address: 
    Jakobi 4, 51005 Tartu
  • Grant Office
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    Faculty address: 
    Lossi 3, III floor, 51003 Tartu
  • Information Technology Office
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  • Human Resources Office
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  • Internal Audit Office
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  • Marketing and Communication Office
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    Ülikooli 18, 50090 Tartu
  • Procurement Office
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    Ülikooli 18a, 51005 Tartu
  • Rector's Strategy Office
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    Faculty address: 
    Ülikooli 18, 50090 Tartu
  • Student Council
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    Ülikooli 18b, 51005 Tartu
  • University of Tartu Press
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    Faculty address: 
    W. Struve 1, 50091 Tartu
Other Units
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  • Tartu Students’ Club
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  • Tartu University Hospital
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  • University of Tartu Foundation
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    Faculty address: 
    Ülikooli 18, 50090 Tartu
  • View all other units

Inaugural lecture by Professor Kalle Kisand on relations between immune system and diabetes mellitus

Professor Kalle Kisand. Photo: Andres Tennus

On Tuesday, 27 March at 16:15, the University of Tartu Professor in Laboratory Medicine delivers his inaugural lecture “Immune system and diabetes mellitus” in the White Hall of the University Museum.

In his inaugural lecture, Professor Kalle Kisand discusses the role of immune mechanisms in the development and course of different forms of diabetes mellitus, including complications. As immune mechanism disorders that lead to diabetes may activate years before the clinical picture of diabetes develops, Professor Kisand also explains the important question of how to assess the risk of prediabetes by means of various biomarkers and gene risks.

Diabetes mellitus is a chronic disease, which involves disorders of the glucose metabolism and emerges if the pancreas does not produce enough insulin or if the organism cannot effectively use the produced insulin. Insulin is a hormone without which cells cannot absorb glucose from the bloodstream. As a result, various biochemical processes in the cells are disturbed, including energy production.

The prevalence of diabetes mellitus in the world is growing, but its causes are not clear yet. The increase in the prevalence of type 2 diabetes mellitus is believed to be associated with lifestyle changes, obesity and metabolic syndrome. Metabolic syndrome is characterised by a higher-than-normal lipid level in blood, elevated blood pressure and low-grade inflammation in the tissues; whereas immune system plays an important role in its development. Type 1 diabetes is even more directly connected with the immune system, because is caused by the body’s own immune cells attacking the cells of the pancreas. The activation of such autoimmune mechanisms destroys insulin-producing pancreas cells and results in insulin deficiency with glucose metabolism disorders.

Kalle Kisand graduated cum laude from Tartu State University in medicine in 1985. After postgraduate studies in Tartu, he defended his dissertation “Development of ELISA for evaluation of autoantibodies of Liver Specific Protein (LSP) in autoimmune liver diseases” in the 2nd Moscow State Medical Institute and was awarded the degree of candidate of medical sciences in allergology and immunology (the third in Estonia). Kalle Kisand has gone through all the stages in a researcher’s career from junior research fellow (1988) to senior research fellow (1994). In spring 2017, he was appointed a professor in laboratory medicine of the University of Tartu.

Professor Kisand has worked on several important research fields in clinical medicine, e.g. infectious diseases, gastroenterology, endocrinology, neurology, rheumatology and orthopaedics. His research topics are closely related with laboratory medicine in order to apply immunological and genetic markers in the diagnostics of diseases, predicting their severity and assessing the risk of their occurrence. Today, Professor Kisand’s research is focused on autoimmune pathogenesis and gene risks of pancreatic disorders and disorders of nervous tissue. In recent years, as a new research topic, he has studied the pathogenesis of osteoarthritis to discover new biomarkers for the early diagnosis of the disease and predict progression risks.  Kalle Kisand also took part in the Helicobacter pylori research led by Professor Kaljo Villako, which received the 1994 annual award of the Ministry of Culture and Education.

Professor Kisand is the founding member of the Estonian Society for Immunology and Allergology and a member of the Estonian Society for Laboratory Medicine. He has more than once been the chair of the Estonian Society for Immunology and president of the Baltic Immunological Society.  Besides research and teaching, Professor Kisand has worked as a coordinator of the Estonian healthcare project led by the Ministry of Social Affairs, and as a World Bank expert in implementing the healthcare project.

 

Additional information: Kalle Kisand, Professor in Laboratory Medicine of the University of Tartu, 731 9341, kalle.kisand [ät] ut.ee

Mari-Liis Pintson
Press Officer
Tel: +(372) 737 5681
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E-mail: mari-liis.pintson [ät] ut.ee
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