Senior Research Fellow of Evolutionary and Population Genomics | University of Tartu

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+372 737 5957
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Lossi 36, 51003 Tartu
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    Lossi 36, 51003 Tartu
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    Ringi 35, 80012 Pärnu
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Ravila 19, 50411 Tartu
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    Biomeedikum, Ravila 19, 50411 Tartu
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    Raekoja plats 6, 51003 Tartu
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    L. Puusepa 8, 50406 Tartu
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    Jakobi 5–205, 51005 Tartu
Faculty of Science and Technology
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Vanemuise 46–208, 51014 Tartu
  • Dean's Office
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    J. Liivi 2, 50409 Tartu
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    Mäealuse 14, 12618 Tallinn
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    Ravila 14a, 50411 Tartu
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    J. Liivi 2, 50409 Tartu
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    Riia 23, 23b–134, 51010 Tartu
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    Vanemuise 46, 51003 Tartu
Institutions
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Support Units
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Contacts of UT units

Faculty of Arts and Humanities
Faculty phone: 
+372 737 5341
Faculty address: 
Jakobi 2, rooms 116–121, 51005 Tartu
  • Dean's Office
    Faculty phone: 
    + 372 737 5341
    Faculty address: 
    Jakobi 2, rooms 116–121, 51005 Tartu
  • Institute of History and Archaeology
    Faculty phone: 
    +372 737 5651
    Faculty address: 
    Jakobi 2, 51005 Tartu
  • Institute of Estonian and General Linguistics
    Faculty phone: 
    +372 737 5221
    Faculty address: 
    Jakobi 2, 51005 Tartu
  • Institute of Philosophy and Semiotics
    Faculty phone: 
    +372 737 5314
    Faculty address: 
    Jakobi 2, rooms 309–352, 51005 Tartu
  • Institute of Cultural Research
    Faculty phone: 
    (+372) 737 5223
    Faculty address: 
    Ülikooli 16, 51003 Tartu
  • School of Theology and Religious Studies
    Faculty phone: 
    +372 737 5301
    Faculty address: 
    Ülikooli 18–310, 50090 Tartu
  • College of Foreign Languages and Cultures
    Faculty address: 
    Lossi 3, 51003 Tartu
  • Viljandi Culture Academy
    Faculty phone: 
    +372 435 5232
    Faculty address: 
    Posti 1, 71004 Viljandi
Faculty of Social Sciences
Faculty phone: 
+372 737 5957
Faculty address: 
Lossi 36, 51003 Tartu
  • Dean's Office
    Faculty phone: 
    + 372 737 5900
    Faculty address: 
    Lossi 36, 51003 Tartu
  • Institute of Education
    Faculty phone: 
    +372 737 6440
    Faculty address: 
    Salme 1a–29, 50103 Tartu
  • Johan Skytte Institute of Political Studies
    Faculty phone: 
    +372 737 5582
    Faculty address: 
    Lossi 36–301, 51003 Tartu
  • School of Economics and Business Administration
    Faculty phone: 
    +372 737 6310
    Faculty address: 
    J. Liivi 4, 50409 Tartu
  • Institute of Psychology
    Faculty phone: 
    +372 737 5902
    Faculty address: 
    Näituse 2, 50409 Tartu
  • School of Law
    Faculty phone: 
    +372 737 5390
    Faculty address: 
    Näituse 20–324, 50409 Tartu
  • Institute of Social Studies
    Faculty phone: 
    +372 737 5188
    Faculty address: 
    Lossi 36, 51003 Tartu
  • Narva College
    Faculty phone: 
    +372 740 1900
    Faculty address: 
    Raekoja plats 2, 20307 Narva
  • Pärnu College
    Faculty phone: 
    +372 445 0520
    Faculty address: 
    Ringi 35, 80012 Pärnu
Faculty of Medicine
Faculty phone: 
+372 737 5326
Faculty address: 
Ravila 19, 50411 Tartu
  • Dean's Office
    Faculty phone: 
    +372 737 5326
    Faculty address: 
    Ravila 19, 50411 Tartu
  • Institute of Biomedicine and Translational Medicine
    Faculty phone: 
    +372 737 4210
    Faculty address: 
    Biomeedikum, Ravila 19, 50411 Tartu
  • Institute of Pharmacy
    Faculty phone: 
    +372 737 5286
    Faculty address: 
    Nooruse 1, 50411 Tartu
  • Institute of Dentistry
    Faculty phone: 
    +372 731 9856
    Faculty address: 
    Raekoja plats 6, 51003 Tartu
  • Institute of Clinical Medicine
    Faculty phone: 
    +372 737 5323
    Faculty address: 
    L. Puusepa 8, 50406 Tartu
  • Institute of Family Medicine and Public Health
    Faculty phone: 
    +372 737 4190
    Faculty address: 
    Ravila 19, 50411 Tartu
  • Institute of Sport Sciences and Physiotherapy
    Faculty phone: 
    +372 737 5360
    Faculty address: 
    Jakobi 5–205, 51005 Tartu
Faculty of Science and Technology
Faculty phone: 
+372 737 5820
Faculty address: 
Vanemuise 46–208, 51014 Tartu
  • Dean's Office
    Faculty phone: 
    +372 737 5820
    Faculty address: 
    Vanemuise 46–208, 51005 Tartu
  • Institute of Computer Science
    Faculty phone: 
    +372 737 5445
    Faculty address: 
    J. Liivi 2, 50409 Tartu
  • Estonian Marine Institute
    Faculty phone: 
    +372 671 8902
    Faculty address: 
    Mäealuse 14, 12618 Tallinn
  • Institute of Physics
    Faculty address: 
    W. Ostwaldi 1, 50411 Tartu
  • Institute of Chemistry
    Faculty phone: 
    +372 737 5261
    Faculty address: 
    Ravila 14a, 50411 Tartu
  • Institute of Mathematics and Statistics
    Faculty phone: 
    +372 737 5860
    Faculty address: 
    J. Liivi 2, 50409 Tartu
  • Institute of Molecular and Cell Biology
    Faculty phone: 
    +372 737 5011
    Faculty address: 
    Riia 23, 23b–134, 51010 Tartu
  • Tartu Observatory
    Faculty phone: 
    +372 737 4510
    Faculty address: 
    Observatooriumi 1, Tõravere, 61602 Tartumaa
  • Institute of Technology
    Faculty phone: 
    +372 737 4800
    Faculty address: 
    Nooruse 1, 50411 Tartu
  • Institute of Ecology and Earth Sciences
    Faculty phone: 
    +372 737 5835
    Faculty address: 
    Vanemuise 46, 51003 Tartu
Institutions
  • Library
    Faculty phone: 
    +372 737 5702
    Faculty address: 
    W. Struve 1, 50091 Tartu
  • Youth Academy
    Faculty phone: 
    +372 737 5581
    Faculty address: 
    Uppsala 10, 51003 Tartu
  • Institute of Genomics
    Faculty phone: 
    +372 737 4000
    Faculty address: 
    Riia 23b, 51010 Tartu
  • Museum
    Faculty phone: 
    +372 737 5674
    Faculty address: 
    Lossi 25, 51003 Tartu
  • University of Tartu Natural History Museum and Botanical Garden
    Faculty phone: 
    +372 737 6076
    Faculty address: 
    Vanemuise 46, 51003 Tartu
Support Units
  • Administrative Office
    Faculty phone: 
    +372 737 5606
    Faculty address: 
    Ülikooli 18a, 51005 Tartu
  • Centre for Entrepreneurship and Innovation
    Faculty phone: 
    +372 737 6339
    Faculty address: 
    Lossi 3, III floor, 51003 Tartu
  • University Office in Tallinn
    Faculty phone: 
    +372 737 6600
    Faculty address: 
    Teatri väljak 3, 10143 Tallinn
  • Estates Office
    Faculty phone: 
    +372 737 5137
    Faculty address: 
    Ülikooli 18a, 51005 Tartu
  • Finance Office
    Faculty phone: 
    +372 737 5125
    Faculty address: 
    Jakobi 4, 51005 Tartu
  • Grant Office
    Faculty phone: 
    +372 737 6215
    Faculty address: 
    Lossi 3, III floor, 51003 Tartu
  • Information Technology Office
    Faculty phone: 
    +372 737 6000, IT-help: +372 737 5500
    Faculty address: 
    Ülikooli 18a, 51005 Tartu
  • Human Resources Office
    Faculty phone: 
    +372 737 5145
    Faculty address: 
    Ülikooli 18, rooms 302 and 304, 50090 Tartu
  • Internal Audit Office
    Faculty address: 
    Ülikooli 17–103, 51005 Tartu
  • Marketing and Communication Office
    Faculty phone: 
    +372 737 5687
    Faculty address: 
    Ülikooli 18, rooms 102, 104, 209, 210, 50090 Tartu
  • Office of Academic Affairs
    Faculty phone: 
    +372 737 5620
    Faculty address: 
    Ülikooli 18, 50090 Tartu
  • Procurement Office
    Faculty phone: 
    +372 737 6632
    Faculty address: 
    Ülikooli 18a, 51005 Tartu
  • Rector's Strategy Office
    Faculty phone: 
    +372 737 5600
    Faculty address: 
    Ülikooli 18, 50090 Tartu
  • Student Council
    Faculty phone: 
    +372 737 5400
    Faculty address: 
    Ülikooli 18b, 51005 Tartu
Other Units
  • University of Tartu Academic Sports Club
    Faculty phone: 
    +372 737 5371
    Faculty address: 
    Ujula 4, 51008 Tartu
  • Tartu Student Village
    Faculty phone: 
    +372 740 9959
    Faculty address: 
    Narva mnt 25, 51013 Tartu
  • Tartu Students’ Club
    Faculty phone: 
    +372 730 2400
    Faculty address: 
    Kalevi 24, 51010 Tartu
  • University of Tartu Press
    Faculty phone: 
    +372 737 5945
    Faculty address: 
    W. Struve 1, 50091 Tartu
  • Tartu University Hospital
    Faculty address: 
    L. Puusepa 1a, 50406 Tartu
  • University of Tartu Foundation
    Faculty phone: 
    +372 737 5852
    Faculty address: 
    Ülikooli 18, 50090 Tartu
  • View all other units

Senior Research Fellow of Evolutionary and Population Genomics

Institute of Genomics
Deadline:
16.09.2019
Duties and responsibilities
We are seeking an experienced and highly motivated researcher in evolutionary genetics, population genetics, computational genetics and genomics or related fields to join an interdisciplinary research group formed through the ERA Chair project Center for Genomics, Evolution and Medicine (cGEM) at the University of Tartu, Estonia. This group, led by cGEM ERA Chair Dr Anders Eriksson, was recently formed with the goal to bridge the fields of bioinformatics, evolutionary biology and genomic medicine. These fields have each undergone explosive growth thanks to recent theoretical and technological advances, but there is a lag in interdisciplinary research, which also contributes to the difficulties in translating basic research results into clinical practice and viable science-based business ideas. The main task of the research group is to, under the supervision of the ERA Chair, unlock and promote synergy both in terms of advancing basic science and technology, and delivering research results that cross the boundaries of established research directions, thereby creating a new frontier of science at the host institution. To this end, the research in the cGEM ERA Chair group will be focussed on combining tools and data from different disciplines to gain insights into the genetic variation, regulatory mechanisms for gene expression and gene-environment interactions responsible for variation in complex human traits and susceptibility to disease within and between and populations, and translating these insights into clinical practise and collaboration with industry.

The cGEM ERA Chair group offers unique opportunities for this research as it is tightly integrated with the Institutes of Genomics (IG) and Clinical Medicine (ICM) at the University of Tartu, with a vibrant and internationally recognised research community and unique resources such as the Estonian national biobank containing 200,000 samples with matching genetic, physiological and health information, a global biobank of over 25,000 human DNA samples from hundreds of populations, as well as modern facilities and equipment, including High Performance Computing cluster (hpc.ut.ee), high-throughput sequencing, ancient DNA facilities, and processing of sample tissue, blood and cell cultures. In addition, the secured funding allows to hire one Junior Research Fellow and one PhD student working under the supervision of the successful applicant.

The main responsibilities of the post hold will be to carry out research and development in evolutionary genetics, population genetics, computational genetics and genomics or related fields; to work with the other members of the groups to unlock synergy between large scale population-based biobank, computational genomics, population and medical genetics in genomics guided evolutionary medicine; and to supervise Junior Research Fellows and PhD students in the group. The post holder will also have an essential role together with the cGEM group leader, PI and the Project Management Board in the selection process during recruitment of Junior Research Fellows and PhD students.

Main tasks of this position are:

• Research, development and creative (RDC) activities in evolutionary genetics, population genetics, computational genetics and genomics or related fields, at least 70% of working time.
• High-level RDC activities, including directing RDC activities in the research theme, taking care that necessary resources are available for it, and taking responsibility for the performance of RDC activities.
• Internationally recognised research in five years at least in the volume equivalent to that of two doctoral theses.
• Supervision of academic staff members involved in RDC activities.
• Participation in the research-organisational activities of international dimension.
• Development of skills necessary for RDC activities, and professional development.
• Teaching and activities related to the administration and development of teaching, up to 20% of working time.
• Teaching, using modern teaching methods and educational technology; primarily supervision of students, incl. doctoral students.
• Professional development to enhance teaching and supervising skills.
• Activities related to the governance and institutional development of the university, at least 5% of working time.
• Social and public activities, at least 5% of working time.
See also job description.
Required qualifications
PhD or an equivalent qualification in a relevant subject, postdoctoral training.
Required experience
Essential skills and experience
• Nationally/Internationally-recognised knowledge and emerging reputation in Genetics/Genomics
• Proven ability to work effectively as part of a team
• Track record of producing publications of outstanding quality
• Track record of contributions to national/international research conferences
• Track record in supervising undergraduate and postgraduate students
• Strong organisational skills
• Excellent communication skills
• Capacity to engage, mentor and motivate colleagues

Desirable skills and experience
• Track record of industry collaboration
• Track record of obtaining funded research projects
• Recognised teaching ability
• Experience in team or project management
Required language skills
Excellent command of English for professional communication and research.
Starting at
01.11.2019, temporary contract to 31.08.2023
Workload
1,00
Salary
According to salary rules of University of Tartu, depending on the candidate's qualification and experience up to 3600EUR/month (before tax)
See also UT salary rules.
Additional info
Candidates are expected to submit: a motivation letter, a research agenda including contacts of two references.

Please do not hesitate contacting:

Dr. Anders Eriksson, cGEM ERA Chair, group leader genomics guided evolutionary medicine, anders.eriksson [ät] kcl.ac.uk
Dr. Mait Metspalu, Institute of genomics, director, PI of the project, maitb [ät] ut.ee
Dr. Andres Salumets, Institute of clinical medicine, WP leader, andres.salumets [ät] ut.ee
Dr. Tõnu Esko, Institute of genomics, head of Estonian Genome Center, tonu.esko [ät] ut.ee
Ms. Merit Kreitsberg, project manager, merit.kreitsberg [ät] ut.ee
Ms. Merilin Raud, assistant, merilin.raud [ät] ut.ee

www.genomics.ut.ee


For the full description of the ERA Chair project and roles of the ERA Chair team members, please contact the contact persons listed above. Here we give a concise summary of the mission, expected impact and tasks of the cGEM ERA Chair project.

General background

The cGEM ERA Chair group aims to apply advancements in genomic medicine in an evolutionarily-aware framework to account for different evolutionary pathways of populations which have led to differences in susceptibility to common diseases. This requires in-depth knowledge about genetic risk factors for diverse ethnic groups, and relevant tools to highlight the underlying genetic predisposition to diseases in complex human populations. For this reason, we will bring together the scientific expertise in three institutions: the Estonian Biocentre (EBC) and the Estonian Genome Center (EGC) which were consolidated to form the Institute of Genomics at the University of Tartu (IGUT) in January 2018, and the Institute of Clinical Medicine (ICM) of the same university. The synergy between the three scientific hubs will create research capacity required for tackling the above mentioned aim. This capacity will be established to apply a holistic approach to understand the evolutionary driving forces that have led to common diseases; develop disease risk prediction models applicable in different populations, and explore the means of translating these findings into a suitable input for everyday clinical practice. All three partners have unique resources such as biobanks, modern facilities and equipment, including high-throughput sequencing, ancient DNA facilities, and processing of sample tissue, blood and cell cultures.

The EGC develops and manages a population-based, longitudinal biobank representing about 20% of Estonia’s adult population (200,000 participants), established in 2000. The whole cohort of the biobank is fully genetically characterized by whole-genome genotyping assays, 3,000 individuals are additionally whole-genome and 2,500 whole-exome sequenced. The data repository is linked with national health registries and hospital databases for up-to-date phenotypic information. The return of individual genomic results (such as polygenic risk scores, high impact alleles and clinically actionable mutations) to biobank donors has started, and strengthening the collaboration with the ICM is instrumental in translating basic research to clinical practice. At the same time, the EBC maintains a sizable sample bank of over 25,000 human DNA samples from hundreds of populations from Eurasia and beyond, which will be critical in establishing the evolutionary driving forces of human complex diseases.